Research Paper Volume 12, Issue 6 pp 5479—5499

Prognostic values of immune scores and immune microenvironment-related genes for hepatocellular carcinoma

Figure 11. External validation of 12 immune-related genes. (A) Pearson correlation of expression and ImmuneScore using GSE62232 dataset. TRBC2 and TRBV28 were not detected. 9 genes, except TMC8, had significant correlation. Y-axis represented expression level of the genes in each sample. (B) Representative immunohistochemical staining images of 7 genes in normal liver tissue and HCC specimen. Images were taken from the Human Protein Atlas (https://www.proteinatlas.org). TMC8 was strongly positive, BIN2, GIMAP7, SPOCK2 were moderately positive, and FYB1, RCSD1, SASH3 were weakly positive in HCC tissues relative to their expression levels in normal liver tissues.