Research Paper Volume 12, Issue 10 pp 8913—8922

HIX003209 promotes vascular smooth muscle cell migration and proliferation through modulating miR-6089

Figure 5. miR-6089 was downregulated in VSMCs induced by inflammatory mediators. (A) miR-6089 expression was downregulated in VSMCs induced by TNF-α compared to control group. (B) ox-LDL can inhibit miR-6089 expression in VSMCs using qRT-PCR analysis compared to control group. (C) The expression of miR-6089 expression in VSMCs was determined by qRT-PCR assay. U6 was used as internal control.