Figure 4. Hsa_circ_0018818 shRNA1 induces apoptosis and inhibits invasion by NSCLC cells. (A, B) The incidence of apoptosis was detected using FACS after double staining cells with Annexin V and PI. X axis: the level of Annexin-V FITC fluorescence; Y axis: the PI fluorescence. (C, D) Transwell assays testing the invasiveness of A549 and NCI-H1650 cells. Magnification: 400×. **P< 0.01 compared to control.