Figure 1. Diversities of the oral microbiota. (A) The α-diversity indexes of bacteria changed with age in various oral sites. (B) The α-diversity indexes of bacteria diverged in different oral sites within each age group. (C) The β-diversity indexes of microbiota changed with age, and the pattern varied in various oral sites. (D) The first principal component analysis revealed microbial changes with age. (E) STEM analysis of the trends of bacterial change over time. In (A) and (C–E), (a) GCF; (b) SAL; (c) TB.