Research Paper Volume 12, Issue 9 pp 7908—7926

Association of tumor growth rates with molecular biomarker status: a longitudinal study of high-grade glioma

Figure 2. The association of molecular biomarkers and tumor growth. (A) The WHO grade was marginally significantly associated with tumor growth in multivariable analysis (p = 0.07). (BF) TERT promoter mutation C250T (p = 0.04), ATRX (p = 0.05) and Ki-67 high expression (p = 0.08), IDH1 mutation (p = 0.06) and MGMT promoter methylation (p = 0.03) showed significant or marginally significant association with tumor growth in univariable analysis but not in multivariable analysis (p > 0.05).