Research Paper Volume 12, Issue 13 pp 12703—12725

Epigenomic and genomic analysis of transcriptome modulation in skin cutaneous melanoma

Figure 2. Identification of SKCM molecular subtypes using CNVcor and METcor genes. (A, B) Plots show the non-negative factorization (NMF) cluster results for CNVcor genes in CNV data (A) and for METcor genes in MET data (B). (C, D) Kaplan–Meier plot analyses of differences in OS among subtypes identified by NMF clustering of CNVcor (C) and METcor (D) genes. (E, F) Subtypes based on CNVcor genes overlapped to a great extent with those based on METcor genes.