Research Paper Volume 12, Issue 9 pp 8049—8066

Growth differentiation factor-11 supplementation improves survival and promotes recovery after ischemic stroke in aged mice

Figure 3. Reduced tissue loss and mortality after exogenous GDF11 treatment in old MCAo mice. (A) survival probabilities, GDF11 treatment led to (B) less brain tissue loss, (C) decrease in cerebrospinal fluid (CSF) area, and preserved (D) corpus callosum (CC) area. An increase in (E) NeuN count and (F) intensity with rGDF11 treatment was seen at 30 days post-stroke. Magnification 20X. Scale bar 20 μm. n=5-8,*p<0.05, **p<0.01.