Figure 3. Reduced tissue loss and mortality after exogenous GDF11 treatment in old MCAo mice. (A) survival probabilities, GDF11 treatment led to (B) less brain tissue loss, (C) decrease in cerebrospinal fluid (CSF) area, and preserved (D) corpus callosum (CC) area. An increase in (E) NeuN count and (F) intensity with rGDF11 treatment was seen at 30 days post-stroke. Magnification 20X. Scale bar 20 μm. n=5-8,*p<0.05, **p<0.01.