Research Paper Volume 12, Issue 9 pp 8067—8083

BMAL1 knockdown triggers different colon carcinoma cell fates by altering the delicate equilibrium between AKT/mTOR and P53/P21 pathways

Figure 8. BMAL1-KD modified the delicate equilibrium between AKT/mTOR and P21/P53 pathways, which triggered the different cell fates based on distinct P53 and circadian rhythm status of every CRC cell line.