Research Paper Volume 12, Issue 9 pp 8107—8119

Nur77 attenuates inflammatory responses and oxidative stress by inhibiting phosphorylated IκB-α in Parkinson’s disease cell model

Figure 5. The effect of cytosporone B and siNur77 on protein expression of phosphorylation of IκB-α. (A, B) MPP+ and siNur77 can increase the level of the phosphorylation IκB-α in MPP+-treated PC12 cells, while CSN-B reverse this increase. (***P < 0.001 compared with control group; $$$P < 0.001, $P < 0.05, compared with MMP+ group; n=3, mean +/- SEM).