Research Paper Volume 12, Issue 9 pp 8301—8320

Long non-coding RNA CCAT1 promotes colorectal cancer progression by regulating miR-181a-5p expression

Figure 4. LncRNA CCAT1 promoted proliferation of HT-29 cells by targeting miR-181a-5p. (A) MTT assay demonstrated that depletion of CCAT1 inhibited cell proliferation. (B, C) The effect of si-CCAT1-1, si-CCAT1-2, miR-181a-5p mimics or miR-181a-5p inhibitor on CRC cell colony formation. *P<0.05, **P<0.01, compared with NC group