Research Paper Volume 12, Issue 9 pp 8301—8320

Long non-coding RNA CCAT1 promotes colorectal cancer progression by regulating miR-181a-5p expression

Figure 6. LncRNA CCAT1 increased migration and invasion capabilities of CRC cells by targeting miR-181a-5p. (A) Scratch-wound healing assay was used to assess the migration potency of HT-29 cells after being transfected. (BD) Relative migration and invasion cell numbers of HT-29 cells transfected with si-CCAT1-1, si-CCAT1-2 or miR-181a-5p mimics detected by transwell assay significantly decreased. *P<0.05, **P<0.01, compared with NC group.