Research Paper Volume 12, Issue 10 pp 9041—9065

Sigma-1 receptor is involved in diminished ovarian reserve possibly by influencing endoplasmic reticulum stress-mediated granulosa cells apoptosis

Figure 3. Apoptotic rate and ERS, mRNA levels of apoptosis-related genes in GCs from patients with DOR. (A) Apoptosis index in patient GCs. (B) The mRNA expression of ERS and apoptosis-related genes was increased in patient GCs. *P<0.05; **P<0.01.