Research Paper Volume 12, Issue 9 pp 8622—8639

Lemon essential oil ameliorates age-associated cognitive dysfunction via modulating hippocampal synaptic density and inhibiting acetylcholinesterase

Figure 3. LEO suppressed accumulation of amyloid protein in the brain. (A, B) Expression of amyloid precursor of APP/PS1 mice. (C) Percentage of positively stained area in the cortex in four groups. (D) Representative photomicrographs of amyloid precursor immunoreactivity in the cortex was compared by one-way ANOVA (P < 0.05). Scale bar = 50 μm. Values are presented as means ± SEM. *P < 0.05, **P < 0.01. LEO: Lemon essential oil.