Research Paper Volume 12, Issue 10 pp 9125—9138

Cigarette smoke-induced lung inflammation in COPD mediated via CCR1/JAK/STAT /NF-κB pathway

Figure 5. Relationships between CCR1 mRNA and cytokine expression levels and FEV1%pred. A negative correlation is observed between CCR1 mRNA levels in the peripheral blood and FEV1%pred in patients with COPD (A). There are significant positive correlations between (B) CCR1 mRNA levels and IL-8, (C) IL-6, (D) MIP-1 (E) α/β, (F) RANTES, (G) SCF, and (H) TNF-α concentrations.