Research Paper Volume 12, Issue 10 pp 9125—9138

Cigarette smoke-induced lung inflammation in COPD mediated via CCR1/JAK/STAT /NF-κB pathway

Figure 6. mRNA expression of CCR1 and downstream pathways in CSE-induced MH-S cells. (A, CE) The RT-qPCR results show that once the CCR1 mRNA expression is inhibited, the CCR1/JAK/STAT3/NF-κB mRNA expression decreased significantly in CSE-induced MH-S cells, (B, F) but not the RANTES and TLR-4 mRNA expression.