Research Paper Volume 12, Issue 9 pp 8680—8701

STAT1-induced upregulation of lncRNA KTN1-AS1 predicts poor prognosis and facilitates non-small cell lung cancer progression via miR-23b/DEPDC1 axis

Figure 4. In vivo mice studies validated that KTN1-AS1 depletion suppressed tumor growth. (A) Relative expression of KTN1-AS1 in A549 and H1299 cells transfected with sh-KTN1-AS1 (sh-KTN1-AS1 #1 or sh-KTN1-AS1 #2) and scrambled shRNA. (B) The photographs and comparison of excised tumor sizes in A549 cells. (C) The tumor volume-time curves. (D) The tumor weights. * P < 0.05, **P < 0.01.