Research Paper Volume 12, Issue 10 pp 9205—9223

Identification of potential novel differentially-expressed genes and their role in invasion and migration in renal cell carcinoma

Figure 3. Univariate survival analysis of hub genes was performed using Kaplan-Meier curves. TIMP1 showed significant differences in both OS (A) and DFS (B) in ccRCC samples (Logrank P < 0.05). (C) Transcriptional levels of TIMP1 expression were found expressed in 533 ccRCC tissues compared with 72 normal tissues (p<0.0001). Abbreviation: DFS: disease-free survival; OS: overall survival; ccRCC: clear cell renal cell carcinoma.