Research Paper Volume 12, Issue 10 pp 9205—9223

Identification of potential novel differentially-expressed genes and their role in invasion and migration in renal cell carcinoma

Figure 8. TIMP1 knockdown inhibited the migration and invasion of A498 and Caki-1 cells. (A) Migration and Matrigel invasion assays of A498 cells transfected with TIMP1 shRNA or NC were evaluated. (C) Migration and Matrigel invasion assays of Caki-1 cells transfected with TIMP1 shRNA or NC were evaluated. (B, D) Migrated and invaded cells were counted in 3 random 100× fields (* p<0.05, ** p<0.01, *** p<0.001 using a t-test).