Research Paper Volume 12, Issue 9 pp 8728ā€”8741

High PRMT5 expression is associated with poor overall survival and tumor progression in bladder cancer

Figure 5. PRMT5 had a strong oncogenic function in bladder cancer. (A) Western blotting showed that PRMT5 was efficiently knocked down by PRMT5-shRNA. (B) Representative images of the tumor xenografts inoculated with T24-shC and T24-sh1 cells and hematoxylin and eosin staining of tumor xenografts are shown. (Cā€“E) Growth curve and histogram analysis of the size and weight of xenograft tumors. Error bars show the standard error of the mean. sh, short hairpin RNA; T24-shC: T24-shRNA/negative control; T24-sh1: T24-shRNA. *P < 0.05, **P < 0.01.