Research Paper Volume 12, Issue 10 pp 9365—9379

Association of cerebrospinal fluid neurogranin levels with cognition and neurodegeneration in Alzheimer’s disease

Figure 4. Baseline CSF Ng levels as the predictor of conversion from CN to MCI. The Kaplan-Meier curve showed the predictive value of the CSF Ng for progression from cognitively normal to MCI. The CSF Ng was analyzed as categorical variables (dichotomized at 389 pg/mL), and analysis was adjusted for age, sex, educational level, and APOE ε4 genotype. Abbreviations: CN, cognitively normal; MCI, mild cognitive impairment; CSF: cerebrospinal fluid; Ng, neurogranin.