Research Paper Volume 12, Issue 10 pp 9549—9584

MiR-1908/EXO1 and MiR-203a/FOS, regulated by scd1, are associated with fracture risk and bone health in postmenopausal diabetic women

Figure 8. miR-1908 inhibits and miR-203a promotes the proliferation and osteogenic differentiation of BM-MSCs. (A) Transfection efficiency of miR-203a and miR-1908 in BM-MSCs. (B) ALP activity was measured in BM-MSCs treated with miRNA inhibitor or mimic (miR-203a and miR1908). (C) The expression of EXO1 and FOS were assessed in BM-MSCs transfected with miR-203a mimic, miR-203a inhibitor, miR-1908 mimic and miR-1908 inhibitor. (D, E) Proliferation of BM-MSCs following the evaluation of the overexpression and knockdown of microRNAs (miR-203a and miR1908).