Research Paper Volume 12, Issue 10 pp 9585—9603

Attenuation of doxorubicin-induced cardiotoxicity by cryptotanshinone detected through association analysis of transcriptomic profiling and KEGG pathway

Figure 6. Top 20 of pathway enrichment statistics based on the differentially expressed gene in the rat hearts after cryptotanshinone (CPT) treatment. Scatter plot of KEGG pathway enrichment statistics (the total number of differentially expressed genes) (A). Scatter plot of KEGG pathway enrichment statistics (the number of differentially expressed genes, which were downregulated (B). p53 signaling pathway in a KEGG map (C). Enrichment score is the ratio of the number of differentially expressed genes to the number of all genes in this pathway term.