Research Paper Volume 12, Issue 10 pp 9585—9603

Attenuation of doxorubicin-induced cardiotoxicity by cryptotanshinone detected through association analysis of transcriptomic profiling and KEGG pathway

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Figure 8. Statistical analysis of the relative protein expression of 14-3-3σ, PI3K p85, p-JNK, p-AKT, cleaved caspase-9, cleaved caspase-3, Bax, Bak, Bim, PUMA, Bcl-xl, and Bcl-2. Semi-qualification of 14-3-3σ, PI3K p85, p-JNK and p-AKT (A). Semi-qualification of Bax, Bak, Bim, PUMA, Bcl-xl, and Bcl-2 (B). Semi-qualification of cleaved caspase-9 and cleaved caspase-3 (C). Both GAPDH and PCNA were used as internal reference. *P<0.05 vs control, #P<0.05 vs DOX.