Research Paper Volume 12, Issue 10 pp 9604—9620

KMT2A regulates cervical cancer cell growth through targeting VDAC1


Figure 5. KMT2A regulated cervical cancer cell migration and apoptosis through targeting VDAC1. Human cervical cancer Siha and Caski cells were transfected with KMT2A shRNAs or KMT2A shRNA + VDAC1 overexpression plasmid. At 48 hours after transfection, the cell migration and apoptosis rates were measured. (A) The migration ability of Siha and Caski cells was measured by wound-healing assay. (B) The cell migration rate %. (C) Apoptosis of Siha and Caski cells was detected by FACS analysis. (D) Annexin V positive cells %.