Research Paper Volume 12, Issue 10 pp 9633—9657

MicroRNA-214-3p targets the PLAGL2-MYH9 axis to suppress tumor proliferation and metastasis in human colorectal cancer

Figure 1. MiR-214-3p is downregulated in CRC tissues and associated with CRC metastasis and proliferation. (A) GEO, Starbase 3.0 (B), and (C) TCGA databases indicated that miR-214-3p is obviously downregulated in CRC. (D) The expression of miR-214-3p was lower in CRC tissues than in adjacent normal tissues. (EF) The expression level of miR-214-3p was negatively correlated with lymph node metastasis and tumor size. (G) MiR-214-3p was significantly lower in CRC cells than in NCM460 cells. The data are represented as the means±S.D. from at least three independent experiments. *p<0.05.