Research Paper Volume 12, Issue 10 pp 9658—9685

Prognostic value of prostaglandin I2 synthase and its correlation with tumor-infiltrating immune cells in lung cancer, ovarian cancer, and gastric cancer

Figure 2. Survival curves of high or low expression of PTGIS in different tumors from the PrognoScan database. (A, B) High PTGIS expression was correlated with better OS and DSS than low PTGIS expression in the breast cancer cohort [GSE1456-GPL96 (n = 159)]. (C, D) High PTGIS expression was correlated with poorer DFS (n = 145) and DSS (n = 177) than low PTGIS expression in the colorectal cancer cohort (GSE17536). (E, F) High PTGIS expression was correlated with poorer OS and DFS than low PTGIS expression in two ovarian cancer cohorts [GSE8841 (n = 81) and GSE26712 (n = 185)]. (G, H) High PTGIS expression was correlated with poorer OS and DSS than low PTGIS expression in a lung cancer cohort (GSE14814, n = 90). OS, overall survival; DFS, disease-free survival; DSS, disease-specific survival.