Research Paper Volume 12, Issue 10 pp 9761—9780

Physiological and metabolic features of mice with CRISPR/Cas9-mediated loss-of-function in growth hormone-releasing hormone

Figure 7. GH-deficiency decreases absolute VO2 and VCO2. VO2 (AD) and VCO2 (EH) values measured on light and dark cycles were averaged. WT female n=12, KO female n=12, WT male n=12, KO male n=11. Each bar represents mean. Statistical analysis was performed by unpaired Student’s t-test with Welch’s correction; ****p<0.0001.