Research Paper Volume 12, Issue 10 pp 9793—9806

Circular RNA hsa_circ_0003141 promotes tumorigenesis of hepatocellular carcinoma via a miR-1827/UBAP2 axis

Figure 4. Downregulation of hsa_circ_0003141 inhibits invasion of HCC cells. (A, B) Huh-7 cells were transfected with hsa_circ_0003141-shRNA1 for 24 h. The invasion ability of Huh-7 cells was measured using transwell invasion assay. (C) Western analysis of E-cadherin, N-cadherin, and α-SMA levels in Huh-7 cells. (DF) The relative expression of E-cadherin, N-cadherin and α-SMA in Huh-7 cells normalized to β-actin. **P < 0.01, compared with the shRNA-NC group.