Research Paper Volume 12, Issue 11 pp 10827—10843

High mutation load, immune-activated microenvironment, favorable outcome, and better immunotherapeutic efficacy in melanoma patients harboring MUC16/CA125 mutations

Figure 1. Mutational patterns of MUC16 and mucin family members in relation to DNA repair-related genes in the TCGA cohort. (A) Numbers of mutations per megabase in each sample. (B) Representation for mutation patterns of mucin and DNA repair genes.