Research Paper Volume 12, Issue 13 pp 12850—12868

Glycosylation end products mediate damage and apoptosis of periodontal ligament stem cells induced by the JNK-mitochondrial pathway

Figure 7. After 72 hours of PDLSCs culture in four different media, apoptosis was detected by flow cytometry detection of AV/PI double staining (A). Each group of cells was pretreated with the JNK pathway inhibitor SP600125 for 30 minutes and then loaded with corresponding stimuli, flow cytometry with Annexin V/PI double staining detected the apoptosis rate of each group (B). Data are presented as the mean±standard deviation (SD) (n=3). (ns P>0.05, * P<0.05, * * P<0.01, *** P<0.001).