Research Paper Volume 12, Issue 13 pp 12850—12868

Glycosylation end products mediate damage and apoptosis of periodontal ligament stem cells induced by the JNK-mitochondrial pathway

Figure 8. (A): mRNA levels and its quantification of JNK, Cyt-c, caspase-3, Bax and BCL-2 expression in different groups which were added inhibitor SP600125 before. (B): Each group of cells was pretreated with SP600125 for 30 minutes and then loaded with corresponding stimuli, and detect the mRNA levels and its quantification of related gene in each inhibitor group. (ns P>0.05, * P<0.05, ** P<0.01, *** P<0.001).