Research Paper Volume 12, Issue 12 pp 12051—12073

Identification of an immune-related long non-coding RNA signature and nomogram as prognostic target for muscle-invasive bladder cancer

Figure 8. PCA (Principal components analysis) and GSEA (Gene set enrichment analysis). PCA based on the eight lncRNAs indicated low-risk and high-risk groups were generally distributed in two different directions in (A) the training cohort and (B) the testing cohort, respectively; (C) PCA based on the whole gene set indicated these two groups did not show significant distinctions; (D, E) GSEA indicated significant enrichment of immune-related phenotype in the high-risk group patients. FDR false discovery rate; NES normalized enrichment score.