Figure 2. Temporal profile of serum antibodies in severe/critical patients with COVID-19. 42 patients had two antibody measurements on day 25 (SD, 7) and on day 27 (SD, 6) post illness onset respectively. (A) IgG titer remained stable during two measurements in both survivors and non-survivors. (B) Change of IgM titer in survivors showed a significantly decreasing (-4 [IQR -14-0], P=0.031), but that in non-survivors didn’t show statistical difference (3 [IQR -19-29], P=0.779).