Research Paper Volume 12, Issue 13 pp 13255—13280

Circular RNA circMBOAT2 promotes prostate cancer progression via a miR-1271-5p/mTOR axis

Figure 3. circMBOAT2 promotes tumorigenesis and metastasis in vivo. (A, B) Images of the xenograft subcutaneous models of PC-3 cells stably transfected with sh-circMBOAT2#1 or sh-NC. (C, D) Tumor volumes and weights of subcutaneous xenograft tumors. (E, F) Representative images of IHC staining and analysis of Ki-67 expression. Scale bars: 100 μm. (G, H) Representative bioluminescence images and analysis of excised lungs from xenograft metastatic models. Data are displayed as mean ± SD. *p < 0.05; **p < 0.01.