Research Paper Volume 12, Issue 13 pp 13281—13296

SLC7A2 serves as a potential biomarker and therapeutic target for ovarian cancer

Figure 9. Effects of SLC7A2 knockdown on the functions of ovarian cancer cell lines. (A) Cell viability increased after SLC7A2 knockdown in the A2780 and OVCAR-3 cell lines. (B) Cell viability had no significant change after SLC7A2 knockdown in the A2780 and OVCAR-3 cell lines cultured in different concentrations of cisplatin for 48 h. (C) Number of colony increased after SLC7A2 knockdown in the A2780 and OVCAR-3 cell lines. (D) Cell invasion and migration increased after SLC7A2 knockdown in the A2780 and OVCAR-3 cell lines. (E) N-cadherin and Vimentin proteins of A2780 and OVCAR-3 cell lines increased after SLC7A2 knockdown. The data are shown as the mean ± SD (n=3). *p < 0.05, **p < 0.01, ***p < 0.001.