Research Paper Volume 12, Issue 13 pp 13281—13296

SLC7A2 serves as a potential biomarker and therapeutic target for ovarian cancer

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Figure 9.

Effects of SLC7A2 knockdown on the functions of ovarian cancer cell lines. (A) Cell viability increased after SLC7A2 knockdown in the A2780 and OVCAR-3 cell lines. (B) Cell viability had no significant change after SLC7A2 knockdown in the A2780 and OVCAR-3 cell lines cultured in different concentrations of cisplatin for 48 h. (C) Number of colony increased after SLC7A2 knockdown in the A2780 and OVCAR-3 cell lines. (D) Cell invasion and migration increased after SLC7A2 knockdown in the A2780 and OVCAR-3 cell lines. (E) N-cadherin and Vimentin proteins of A2780 and OVCAR-3 cell lines increased after SLC7A2 knockdown. The data are shown as the mean ± SD (n=3). *p < 0.05, **p < 0.01, ***p < 0.001.