Research Paper Volume 12, Issue 13 pp 13400—13421

Penehyclidine hydrochloride inhibits renal ischemia/reperfusion-induced acute lung injury by activating the Nrf2 pathway

Figure 5. Effects of PHC on rI/R-induced lung oxidative stress in rats. (A, B) Myeloperoxidase (MPO) production in the lungs was analyzed using immunohistochemistry and an ELISA. (CE) ELISAs were used to analyze malondialdehyde (MDA), glutathione (GSH) and SOD concentrations in lung homogenates. Data are presented as the mean ± S.D. (n = 8, Scale bar: 50 μm). *P < 0.05, **P < 0.01 vs. the sham group. #P < 0.05, ##P < 0.01 vs. the rI/R group.