Research Paper Volume 12, Issue 13 pp 13668—13683

CAMKIIγ is a targetable driver of multiple myeloma through CaMKIIγ/ Stat3 axis


Figure 4. CaMKIIγ was essential for MM tumorigenesis in vivo. (A, D) CaMKIIγ overexpression or knockout was validated by Western blot. (B, E) Representative images of xenograft tumors from the indicated groups. BALB/C nude mice were injected subcutaneously in the left groin with 1.5x10^7 KM3 or U266 cells. Tumor blocks were removed from the mice at 3 weeks after inoculation. (C, F) Tumor weight in indicated groups (*P < 0.05, ***P < 0.001).