Research Paper Volume 12, Issue 13 pp 13701—13715

Exome sequencing identifies somatic mutations in novel driver genes in non-small cell lung cancer

Figure 1. Next-generation sequencing in NSCLC. (A) Percentages of non-silent somatic single nucleotide variants identified by next-generation sequencing (whole-genome/whole-exome/targeted sequencing) in 13 NSCLC patients. (B) Numbers and types of non-silent somatic mutations. (C) Mutations identified by next-generation sequencing in 13 NSCLC patients and in a validation group of 88 NSCLC patients. The type of each mutation is shown for every sample, and the number of subjects (n) with mutations is listed on the right. AC, lung adenocarcinoma. SCC, lung squamous cell carcinoma. ASCC, lung adenosquamous carcinoma.