Research Paper Volume 12, Issue 13 pp 12517—12533

Untargeted metabolomics for uncovering biological markers of human skeletal muscle ageing

class="figure-viewer-img"

Figure 2.

Representative boxplots of metabolite abundance for metabolites A) 2423 and B) 2104 which were selected via RF to be predictive of muscle age and were matched to a number of steroid and androgen metabolites following annotation using the PIUMet algorithm. Relative abundance for both metabolite features shows decline with age, a well-established relationship observed in ageing muscle for steroid and androgen metabolites.