Research Paper Advance Articles

Untargeted metabolomics for uncovering biological markers of human skeletal muscle ageing

Figure 2. Representative boxplots of metabolite abundance for metabolites A) 2423 and B) 2104 which were selected via RF to be predictive of muscle age and were matched to a number of steroid and androgen metabolites following annotation using the PIUMet algorithm. Relative abundance for both metabolite features shows decline with age, a well-established relationship observed in ageing muscle for steroid and androgen metabolites.