Figure 1. Expression levels of GFAP and GJA1 encoding for Cx43 in human sALS biopsies. (A, B) mRNA expression levels of GFAP (A) and GJA1 (B) in the central nervous system of sALS patients versus healthy control levels. Data are expressed as z-score intensity expression levels and presented via standard Box and whiskers plot. ****p-value < 0.0001 and *p-value < 0.05 versus healthy control group. (C) Linear regression analysis of GFAP and GJA1 z-scores in sALS group.