Research Paper Volume 12, Issue 13 pp 12598—12608

Increased expression of connexin 43 in a mouse model of spinal motoneuronal loss

Figure 2. Motor impairment in spinal motoneuronal depleted CTB-Sap mice. (A) Experimental setting of open field grid walk behavioural platform. (B, C) Representative tracks (B) and quantification of the number of footfalls over meter (C) of healthy (black) and CTB-Sap lesioned (red) mice at 0, 7, 21 and 42 days post-lesion (dpl); data are mean ± SEM; **p-value < 0.01 and *p-value < 0.05 versus healthy control group. (D) Clinical score of CTB-Sap-lesioned mice in the time course of lesion; data are mean ± SEM.