Research Paper Volume 12, Issue 20 pp 20095—20110

Depressive and anxiety disorders worsen the prognosis of glioblastoma

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The expression pattern of mesenchymal and epithelial markers in both groups. (A) Western blotting assay showed significantly higher expression of CD44 and Vimentin, and lower expression of Sox1 and E-cadherin in GBM cells from higher scored group than lower scored group. α-tubulin was used as internal reference. (B) Bar charts showed the relative expression of these markers to α-tubulin and revealed the statistically different expression of these markers between two groups.