Research Paper Volume 12, Issue 21 pp 21114—21128

Hsa_circ_0043278 functions as competitive endogenous RNA to enhance glioblastoma multiforme progression by sponging miR-638

Figure 2. Knockdown circ_0043278 inhibits glioma cell migration and invasion. (A, B) Transwell assay results for U87 and U251 glioma cell invasion and migration. Results represent the mean±SD for three independent experiments (*p<0.05, **p<0.01, as determined by one-way ANOVA with Dunnett’s multiple comparisons test). NC, negative control. Scale bar = 50 μm in all panels.