Research Paper Volume 12, Issue 21 pp 21114—21128

Hsa_circ_0043278 functions as competitive endogenous RNA to enhance glioblastoma multiforme progression by sponging miR-638

Figure 4. Overexpression of miR-638 promotes glioma cell migration and invasion. (A, B) U87 and U251 glioma cells were transfected with miR-638 mimics, and both cells migration and invasion were determined using transwell assays. Results represent the mean±SD for three independent experiments (**p<0.01; as determined by unpaired Student’s t-test). Scale bar = 50 μm in all panels.