Research Paper Volume 12, Issue 15 pp 15581—15602

hsa_circRNA6448-14 promotes carcinogenesis in esophageal squamous cell carcinoma

Figure 1. CircRNAs expression profiles in ESCC and adjacent normal tissues. (A) Hierarchical clustering showed that a large number of circRNAs were expressed in two groups. (B) Correlation analysis showed a high correlation of samples. (C) Box plots showed that samples had comparable intensities. (D) Three-dimensional principal component analysis (PCA 3D) indicated high similarity of samples.