Research Paper Volume 12, Issue 15 pp 15603—15623

Transcriptome analysis of mouse aortae reveals multiple novel pathways regulated by aging

Figure 6. qRT-PCR validation of representative genes for major age-regulated terms/pathways. qRT-PCR analysis for the representative genes involving in (A) ECM organization, (B) protein folding and (C) circadian rhythm in young versus old mouse aortae. Data are presented as a scatterplot of individual points with mean±SD, reflecting fold changes over young aortae (set to 1), n=5. *p < 0.05, **p < 0.01, unpaired two-tailed Student's t-test.