Research Paper Volume 12, Issue 15 pp 15603—15623

Transcriptome analysis of mouse aortae reveals multiple novel pathways regulated by aging

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Figure 8. Proposed model of transcriptome regulated by arterial aging. Schematic illustrating that arterial aging triggers the activation of inflammatory response and reduction of ECM fibril organization, chaperon-mediated protein folding control and stress response, as well as altered circadian clock.