Research Paper Volume 12, Issue 15 pp 15603—15623

Transcriptome analysis of mouse aortae reveals multiple novel pathways regulated by aging

Figure 8. Proposed model of transcriptome regulated by arterial aging. Schematic illustrating that arterial aging triggers the activation of inflammatory response and reduction of ECM fibril organization, chaperon-mediated protein folding control and stress response, as well as altered circadian clock.