Research Paper Volume 12, Issue 15 pp 15638—15655

Protection of procyanidin B2 on mitochondrial dynamics in sepsis associated acute kidney injury via promoting Nrf2 nuclear translocation

Figure 2. Effects of PB2 on mitochondrial structure and mitochondrial-mediated apoptosis (n = 8). Mitochondrial structure in renal tubular epithelial (Bar = 1 μm) (A); TUNEL staining (Bar = 50 μm, green fluorescent spots) (B), and percentage of TUNEL-positive cells (C); expressions of caspases, Bcl-2, Bax, VDAC1, Cyt c and the semi-quantification (DF). #P ≤ 0.05, ##P ≤ 0.01 compared to control mice; *P ≤ 0.05, **P ≤ 0.01 compared to LPS challenged alone.