Research Paper Volume 12, Issue 15 pp 15638—15655

Protection of procyanidin B2 on mitochondrial dynamics in sepsis associated acute kidney injury via promoting Nrf2 nuclear translocation

Figure 7. Improved mitochondrial dynamics depend on Nrf2 translocation (n = 8). Mice in co-treatment group were treated with brustatol 24h prior LPS challenge in i.p.. The mitoSox red (Bar = 50 μm) (A); expressions of total and nuclear Nrf2, VDAC1 and Cyt c (B), OPA1 and Drp1, Bax and caspase-3 and semi-quantification (C). #P ≤ 0.05, ##P ≤ 0.01 compared to control mice; *P ≤ 0.05, **P ≤ 0.01 compared to LPS challenged alone; P ≤ 0.05, ▲▲P ≤ 0.01 between PB2 and PB2+BT.