Research Paper Volume 12, Issue 15 pp 15638—15655

Protection of procyanidin B2 on mitochondrial dynamics in sepsis associated acute kidney injury via promoting Nrf2 nuclear translocation

Figure 8. Improved mitophagy depend on Nrf2 translocation (n = 8). Mitochondrial structure in renal tubular epithelial (Bar = 5 μm) (A); co-localization of anti-Pink1 (green)/anti-COX IV (red) antibodies (B) (Bar = 25 μm); the co-localization fluorescence intensity, overlap coefficient and Pearson's correlation of Pink1-COX IV (C); expressions of Pink1, parking, LC3, p62, TOM20 and TIM23, semi-quantification (DF). #P ≤ 0.05, ##P ≤ 0.01 compared to control mice; *P ≤ 0.05, **P ≤ 0.01 compared to LPS challenged alone; P ≤ 0.05, ▲▲P ≤ 0.01 between PB2 and PB2+BT.