Research Paper Volume 12, Issue 15 pp 15638—15655

Protection of procyanidin B2 on mitochondrial dynamics in sepsis associated acute kidney injury via promoting Nrf2 nuclear translocation

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Figure 8.

Improved mitophagy depend on Nrf2 translocation (n = 8). Mitochondrial structure in renal tubular epithelial (Bar = 5 μm) (A); co-localization of anti-Pink1 (green)/anti-COX IV (red) antibodies (B) (Bar = 25 μm); the co-localization fluorescence intensity, overlap coefficient and Pearson's correlation of Pink1-COX IV (C); expressions of Pink1, parking, LC3, p62, TOM20 and TIM23, semi-quantification (DF). #P ≤ 0.05, ##P ≤ 0.01 compared to control mice; *P ≤ 0.05, **P ≤ 0.01 compared to LPS challenged alone; P ≤ 0.05, ▲▲P ≤ 0.01 between PB2 and PB2+BT.